RAF Typhoon FGR4s have joined forces with French aircraft in a combined operation targeting an hidden munitions depot in Syria employed by the IS group, per a report from the British defence ministry.
The location, pinpointed through surveillance, was believed to be storing arms and explosives, the statement said, and was located in hills just above the historic site of Palmyra in the heart of Syria.
"Our aircraft employed laser-guided Paveway IV weapons to hit a number of approach shafts down to the facility... early reports are that the objective was successfully hit," officials stated.
There was no evidence of any civilian casualties in the strike conducted Saturday night and every plane involved returned safely, the MoD added.
The Typhoon FGR4s were supported by a Voyager tanker plane.
Daesh - also known as ISIS - enforced jihadist rule over large swathes of Iraq and Syria prior to its 2019 collapse.
"This action shows the UK's leading role, and resolve to work closely with our partners, to eradicate any re-emergence of IS and their harmful and extremist ideologies in the Middle East," Britain's Defence Chief John Healey remarked.
UK warplanes have conducted patrols over Syria to "deter any efforts to regroup" of Islamic State after its defeat at the climactic battle in Baghuz in the year 2019, the ministry said.
"I extend gratitude to every member of our armed forces who took part in this strike for their professionalism and their courage," he said. "They were among a great many British troops on duty over Christmas and New Year. This action, to remove militants who threaten our way of life, demonstrates how our armed forces are prepared to act, throughout the year, ensuring Britain's security within its borders and influential overseas."
In December, the American forces conducted what it described as a "major assault" against Islamic State objectives in the country, after an attack claimed the lives of two US servicemembers and a local interpreter in the Palmyra area.
The UN reports Daesh still maintains roughly 5-7 thousand fighters in both countries.